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Each sample comprises unrelated healthy donors from whom appropriate informed consent was obtained.
The ethical clearance for the study was obtained from the organizational ethical clearance committee of Anthropological Survey of India.
DNA was extracted from all the collected 4–5 ml blood samples using standard phenol-chloroform methods .
PCR product was sequenced with both forward and reverse primers using Big Dye Terminator v3.1 sequencing kits from Applied Biosystems on an Applied Biosystems 3730 automated DNA analyzer.
Our results showing a shared mt DNA lineage between Indians and Australian Aborigines provides direct genetic evidence of an early colonization of Australia through south Asia, following the "southern route".
) begins in Africa with a group of hunter-gatherers, perhaps just a few hundred strong and ends some 150 – 200 thousand years (ky) later with their six and a half billion descendants spread across the occupied world.
Our other complete mt DNA sequences under publication elsewhere can also be found at Gen Bank with accession numbers FJ383174–FJ383814.
This work is essentially a part of the Anthropological Survey of India's project "DNA Polymorphisms in Contemporary Indian Populations and Ancient Skeleton Remains" we express our gratitude to the Ministry of Culture, Government of India for supporting the project. Curran for her suggestions in improving the manuscript.
SK, RRR and PK carried out initial screening and complete mt DNA sequencing of the data. VRR conceived the study, participated in its design and coordination also helped to improve the manuscript.Likewise, support from the archaeology is still ambiguous.In our completely sequenced 966-mitochondrial genomes from 26 relic tribes of India, we have identified seven genomes, which share two synonymous polymorphisms with the M42 haplogroup, which is specific to Australian Aborigines.PL numbers link to slip law texts after they have been published by GPO. R.4374 - To amend the Federal Food, Drug, and Cosmetic Act to authorize additional emergency uses for medical products to reduce deaths and severity of injuries caused by agents of war, and for other purposes.
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